Cheese was the subject of A Cheesy Episode. His temper was extremely short when Orange made fun of him. Cheese strongly hated Orange since they firstly met. Orange then proceeded to say puns until Cheese finally snapped and wished to die. He became overjoyed when Dane Boedigheimer grated him. Unfortunately for him, he is baked onto a pizza, and cries in agony as Orange begins to annoy him again.
- Tobuscus, who voiced Cheese, did a remix of The Annoying Orange. (The video has an annotation at the end for "his cheesy cameo" much like The Annoying Orange series).
- He is the first character in the series with a short temper.
- He is the first character to be happy to die, as Orange's annoyance drove him suicidal.
- He is probably Mozzarella cheese, as it is the traditional cheese to use in pizzas, one in which Cheese was baked into.
- He is the first food that wasn't a fruit or vegetable to appear in the series.
- "Say that one more time, and I swear I'm gonna hurt you!"
- "(pretends to laugh) Shut it!"
- "Look I'm not playing your game, okay?"
- "Who told you puns are funny? Cause they're not!"
- "I hate you, and I hate your stupid puns."
- "That's it! I'm not listening to anymore puns."
- "Not listening, lalalalalala..."
- "Oh, stop. stop."
- "No let's not do it again, ever!"
- "Aaah!!!! I can't take it!!! Someone end this right now!!! I can't take any more stupid puns!!!"
- "Yes! I am so out of here!"
- "Thank you! Ahhh! Oww! Ahhh! Thank you, End my misery!"
- "No more puns, no more pu-ahh!"
- "I regret nothing! Haha, nothing!!"